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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on January 23, 2003, at 17:45:44
Do different AD's have differences in their likelyhood to cause mania. Does anyone know
if this info is available anywhere.Linkadge
Posted by catmint on January 23, 2003, at 19:06:31
In reply to Relative AD mania likelyhood ?, posted by linkadge on January 23, 2003, at 17:45:44
Zoloft caused a euphoric mania in me, Prozac did not. Wellbutrin caused a dysphoric(sp?) mania.
Posted by Ritch on January 24, 2003, at 1:20:36
In reply to Relative AD mania likelyhood ?, posted by linkadge on January 23, 2003, at 17:45:44
> Do different AD's have differences in their likelyhood to cause mania. Does anyone know
> if this info is available anywhere.
>
> LinkadgeYes, they do, but unfortunately that is very individual. Some BP's are super-sensitive to SSRI's, others TCA's, others ANY AD, etc. I find it mostly a dose-related sensitivity issue for any of them (in my experience). It really depends on your experience with the different AD's, all else being equal (concurrent meds).
Posted by Maximus on January 24, 2003, at 12:19:42
In reply to Re: Relative AD mania likelyhood ? » linkadge, posted by Ritch on January 24, 2003, at 1:20:36
> Do different AD's have differences in their likelyhood to cause mania. Does anyone know
> if this info is available anywhere.Yes that is very very individual. But in general the biggest "culprit" is the norepinephrine. It is the biggest trigger. So it is wishable to avoid TCAs and take them only as a last resort.
On the other hand, TCAs, SSRIs or others, you have to take a mood stabilizer *anyway* with them if you're bipolar.
Max.
Posted by Nala on January 25, 2003, at 14:36:32
In reply to Relative AD mania likelyhood ?, posted by linkadge on January 23, 2003, at 17:45:44
> Do different AD's have differences in their likelyhood to cause mania. Does anyone know
> if this info is available anywhere.
>
> LinkadgeLindadge,
Currenlty diagnosed as BP II. Remeron (worst of the lot for me) caused "dyphoric mania", Serzone slight euphoric mainia, Wellbutrin: poss, "aggitated mania", Celexa extreme euphoric mania, and Zoloft, no mania. I agree, it's usually a personal reaction.
Posted by judy1 on January 26, 2003, at 11:55:48
In reply to Relative AD mania likelyhood ?, posted by linkadge on January 23, 2003, at 17:45:44
I think the other posters addressed the most likely culprits. I have bp1 and any AD will throw me into a manic reaction (even the AED lamictal with its AD properties). Even worse than the manic episode is the rapid cycling (now in its' 3rd year) that I developed from taking prozac. Some studies mention wellbutrin as the least likely AD to induce mania, but that wasn't the case for me. So even on mood stabilizers, I realize I can't take any AD w/o adverse effects. take care, judy
This is the end of the thread.
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