Psycho-Babble Medication Thread 579325

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Trazodone vs Desyrel?

Posted by AX on November 16, 2005, at 12:09:27

A short history: A few years ago I was taking Desyrel. Worked wonderfully - depression lifted, motivation returned - absolutely no downside. After about a year, however, it pooped out. So I tried the generic, trazodone, but that didn't work either. Previously, I had been prescribed SSRIs but found I couldn't take them - lots of undesirable side effects. After trazodone, I was prescribed Wellbutrin which sort of worked but not nearly as successfully as Desyrel. Also tried Effexor with horrible results. Medical history probibits tricyclics or MAO inhibiters.

A few months ago, I began experiencing panic attacks and asked my internist for trazodone (can't afford Desyrel). Suprisingly, it's been horrible! I began with 50 mg, and had trouble sleeping and a slight headache. After three nights, I increased the dose to 100 mg and was restless, had a horrible headache and congestion, and felt frantic and weepy. Last night, I dropped it back to 50 mg - side effects were less severe. Previously, I had taken 150 mg Desyrel.

What's going on?? Is it the generic that makes the difference (the manufacturer is Pliva)? I'm not sure what to do. As I said, Desyrel was GREAT. Within just a couple of weeks I felt like a different person. Should I simply give it more time?

 

Re: Trazodone vs Desyrel?

Posted by med_empowered on November 17, 2005, at 2:21:04

In reply to Trazodone vs Desyrel?, posted by AX on November 16, 2005, at 12:09:27

This happens sometimes. Drug X works for a while, then stops..upping the dose doesn't help. I dont think it has to do with med being generic; I guess you could up the dose a bit if you think that's the case, but I don't know how much good that will do. You might want to try a combo strategy, rather than doing 1-med therapy. SSRIs+Wellbutrin works pretty well; you can avoid some of the SSRI side effects that way. Remeron also helps alot of people, and can be combined with other stuff (ex: wellbutrin, effexor, cymbalta) if necessary. Depending on your symptoms, other medications--mood-stabilizers, stimulants, benzos--may also be helpful with handling your depression.


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