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Dr. Bob is Robert Hsiung, MD,
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Posted by JayBTV on January 4, 2007, at 10:33:13
I know Desipramine is a metabolite of Imipramine and therefore your body gets some Desipramine when taking Imipramine.
My question is if there is a percentage of the MG dose of Imipramine that breaks down into Desipramine your body uses. For example I'm taking 150mg of Imipramine - is there an approximate mg amount of Desipramine I could assume my body is getting from that 150mg of Imipramine? In other words does the metabolite equate to a comparable amount of the regular drug....
Hope that's not too wordy but I'd appreciate any insight.
Cheers,
-Jay
Posted by SLS on January 4, 2007, at 12:39:01
In reply to How much Desipramine do you get from Imipramine?, posted by JayBTV on January 4, 2007, at 10:33:13
Hi Jay.
> I know Desipramine is a metabolite of Imipramine and therefore your body gets some Desipramine when taking Imipramine.
Imipramine is quickly and extensively metabolized into desipramine. I can't give you an exact number, but once equilibrium is established, there is significantly more desipramine in the bloodstream than imipramine.
- Scott
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