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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by dbc on March 18, 2008, at 13:37:55
I guess im a statistic now because im one of the few people ever to have paranoid hallucinations/delusions from lamictal. As far as i know this is limited to 3 other people. Heres the odd part its totally dose dependent at exactly 100-125mg daily is when i was totally losing my mind.
I didnt fully disclose how insane i was being and my doctor just prescribed an Atypical and it did nothing. The even odder part is that as soon as i upped the dose to 150 and eventually 200 the psychotic symptoms faded away. I have absolutely no history of hallucinations aside from once that involved pyshostimulants (oh dexedrine you cruel mistress). But other than that i've been free of hallucinations/delusions/true insanity.
So yes folks im a statistic also the lamictal has definetly effected my cognitive ability to compose a sentence and spell so forgive me if the post seems off.
Posted by Phillipa on March 18, 2008, at 13:45:01
In reply to Im an anomaly (lamictal crazyness), posted by dbc on March 18, 2008, at 13:37:55
Your post is fine are you doing better now? Phillipa
Posted by dbc on March 18, 2008, at 14:12:35
In reply to Re: Im an anomaly (lamictal crazyness) » dbc, posted by Phillipa on March 18, 2008, at 13:45:01
I feel relatively normal for me. I think im finally giving up my valium (10mg/as needed) for my panic/generalized anxiety.
My theory as to why the lamictal set off psychotic symptoms involves some research that was done on NMDA receptors and their glutamate levels in relation to hallucinations in psychosis/schizophrenia. The main function of lamictal is to block glutamate (the brains primary excitatory amino acid).
The hallucinations always seemed to happen at night so my guess is that since lamictal has such a wide variability in its bioavability (ie its different for every single person) what was going on was that my blood levels of lamictal were dropping causing a general surge of glutamate which of course affected certain NMDA receptors and i went nuts. So when i increased the dose it increased bioavailability and psychosis subsided.
Of course theres no way to prove this and no one is going to put the research into seeing if their product makes people well...flip the hell out unless theres substantial cases.
And yes im fine now aside from very minor visual things such as stationary objects looking like they're moving (vibrating) for a second but thats so minor it doesnt disturb me.
Posted by Phillipa on March 18, 2008, at 19:18:23
In reply to Re: Im an anomaly (lamictal crazyness), posted by dbc on March 18, 2008, at 14:12:35
Not well versed myself in the mechanisms of the meds but glad you figured it out and are feeling better. Phillipa
Posted by Jeroen on March 20, 2008, at 10:23:31
In reply to Im an anomaly (lamictal crazyness), posted by dbc on March 18, 2008, at 13:37:55
hi this stuff gave me a psychosis after 3 days on it, i think youre experiencing the same thing, i recommend you try Abilify or Seroquel
my paranoid reaction was gone when i took a small dose of abilify, ... i hope it helps
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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