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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by JayBTV2 on January 1, 2010, at 23:06:48
I just started a trial of Parnate and so far things are going pretty well.
Just curious though why when it comes to MAOIs people here try either Parnate or Nardil. When I started Parnate my pDoc gave me a dietary restriction card put out by the generic makers of Marplan. I read here often and hardly ever hear it talked about - so much so that I thought it was off the market. Parnate and Nardil threads are quite common on the other hand....
Is there a reason it appears to be the so unpopular among the 3?
Thanks for any info or anecdotes....
-Jay
Posted by Bob on January 2, 2010, at 0:21:56
In reply to Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 1, 2010, at 23:06:48
Posted by willey on January 2, 2010, at 5:54:42
In reply to Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 1, 2010, at 23:06:48
Heres the maoi low down.Google has a new feature to search news articles in history.
So i read one about maois.Sometime in the 60`s,shortly after the realease,people started to die,and after evalution it was found the maois were to blame with food interactions.
All were quickly pulled of the market comptly.Luckly a few years later they were re interoduced,HOWEVER not willing so,they realesed as a LAST OPTION plan,they were to be used only as a last resort and even then so used under docs direct supervision.
The main two re relaesed were parnate and nardil.Which is why u hear mostly about them.Were actualy lucky were given maois,after reading that we came close ,very close to never have seeing maois.
But this is where the neglect to use them stems from.
Marplan wasnt one of the mainstream ones to be re released,and ill tell you personaly unless u have a willing doc,um it will BE HARD to get it.
If i remeber correctly,paper had to be sent to my doc,a lot for a doc to fill out,my doc then had to make a call,my pharmacy had to set up what thay call a drop shipment.
So because of the enourmous hurdles its prob very unlikly a common p doc will go through this for a drug that was already removed of the market.
Posted by SLS on January 2, 2010, at 6:26:40
In reply to Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 1, 2010, at 23:06:48
> Just curious though why when it comes to MAOIs people here try either Parnate or Nardil. When I started Parnate my pDoc gave me a dietary restriction card put out by the generic makers of Marplan. I read here often and hardly ever hear it talked about - so much so that I thought it was off the market. Parnate and Nardil threads are quite common on the other hand....
>
> Is there a reason it appears to be the so unpopular among the 3?Marplan has a reputation for being less effective than Nardil and Parnate. It is considered to be a "weak Nardil". I don't know that there is any scientific evidence to support this notion. There are some people who respond well to Marplan whom had not responded to Parnate or Nardil. Marplan is usually better tolerated than Nardil with respect to side effects.
- Scott
Posted by Maxime on January 2, 2010, at 8:20:16
In reply to Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 1, 2010, at 23:06:48
It's not available in Canada and that is why I am on Parnate. I would have liked to have tried it.
Posted by JayBTV2 on January 2, 2010, at 10:50:30
In reply to Re: Why is Marplan overlooked as an MAOi -Experiences? » JayBTV2, posted by SLS on January 2, 2010, at 6:26:40
> > Just curious though why when it comes to MAOIs people here try either Parnate or Nardil. When I started Parnate my pDoc gave me a dietary restriction card put out by the generic makers of Marplan. I read here often and hardly ever hear it talked about - so much so that I thought it was off the market. Parnate and Nardil threads are quite common on the other hand....
> >
> > Is there a reason it appears to be the so unpopular among the 3?
>
> Marplan has a reputation for being less effective than Nardil and Parnate. It is considered to be a "weak Nardil". I don't know that there is any scientific evidence to support this notion. There are some people who respond well to Marplan whom had not responded to Parnate or Nardil. Marplan is usually better tolerated than Nardil with respect to side effects.
>
>
> - Scott
>
>Got ya. I just find it weird that it seems like it's never used. Especially since Validus Pharmaceuticals is pushing it a bit (Re: the info card I got from my doctor was printed by them).
Another example is on askapatient.com where Marplan only has 2 reviews. On the other hand Parnate has 58 reviews - Nardil has 48.
Would love to hear any personal success stories with it. I've been on Nardil before but it made me manic (to be fair I took way more than I was supposed to - might have been manic prior - was taking a few other meds).
Like I said I'm currently trying Parnate (low dose since my doc is afraid of my manic side). So far it seems to be helping but was wondering if Marplan would be a good Plan-B in the event Parnate doesn't work out.
Thanks for all the insight guys - happy 2010!!
-Jay
Posted by Phillipa on January 2, 2010, at 12:42:11
In reply to Re: Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 2, 2010, at 10:50:30
Sounds like it could be an option for a person that doesn't need the strength of nardil or parnate or can't tolerate them. Phillipa
Posted by stargazer2 on January 3, 2010, at 20:24:12
In reply to Why is Marplan overlooked as an MAOi -Experiences?, posted by JayBTV2 on January 1, 2010, at 23:06:48
I took Marplan successfully until it was discontinued by Roche in 1993. It was the last MAO that was successful for me. Following that I tried Parnate unsuccessfully and every other AD that was released between 1993 and probably 2003. Nardil worked successfully prior to Marplan and then when I retried it, it did not. Marplan has recently(in the last 2-3 years) been rereleased. My trial with it a year or two ago failed, but I would retry again in the future, if necessary.
In my opinion, I would try any MAO multiple times before ruling them out. Perhaps, Marplan might be the one that could help you.
This is the end of the thread.
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